Para-bile-osis Establishes a Role for Nonbiliary Macrophage to Feces Reverse Cholesterol Transport
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چکیده
منابع مشابه
Para-bile-osis Establishes a Role for Nonbiliary Macrophage to Feces Reverse Cholesterol Transport.
Elimination of excess cholesterol by the reverse cholesterol transport (RCT) pathway opposes atherosclerotic cardiovascular disease. RCT begins with the mobilization of excess free cholesterol from macrophage foam cells in the artery wall to high-density lipoproteins. After esterification of cholesterol in the plasma compartment by lecithin cholesterol:acyltransferase, cholesteryl esters can be...
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Liver X receptor (LXR) activation promotes reverse cholesterol transport (RCT) in rodents but has major side effects (increased triglycerides and LDL-cholesterol levels) in species expressing cholesteryl ester transfer protein (CETP). In the face of dyslipidemia, it remains unclear whether LXR activation stimulates RCT in CETP species. We therefore used a hamster model made dyslipidemic with a ...
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ژورنال
عنوان ژورنال: Arteriosclerosis, Thrombosis, and Vascular Biology
سال: 2017
ISSN: 1079-5642,1524-4636
DOI: 10.1161/atvbaha.117.309224